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KMID : 0388019940050040029
Korean Journal Gynecologic Oncology and Colposcopy
1994 Volume.5 No. 4 p.29 ~ p.38
Two Cases of Glassy cell Carcinoma of the Cervix, Treated by Neoadjuvant Chemotherapy and Radical Hysterectomy
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Abstract
Glassy cell carcinoma is a histologic subtype of cervical cancer with distinct pathologic features and it has an aggressive biologic course.
It was first described by Glucksmann and Cherry in 1956 as a poorly differentiated adenoquamous carcinoma and commented o its poor prognosis, unresponsiveness to traditional modes of therapy, and often associated with pregnancy.
The characteristic histologic features are defined as follow: 1) cells with a moderate amount of cytoplasm resembling ground glass, 2) a fairly distinct cell membrane that stains with eosin or PAS, 3) large nuclei with prominent nucleoli.
We present two cases of glassy cell carcinoma of the cervix, successfully treated by neoadjuvant chemotherapy and radical hysterectomy, with a brief review of literatures.
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